1. Gene
  2. Sod3 - superoxide dismutase 3 Gene

Sod3 - superoxide dismutase 3 Gene

种属: Rattus norvegicus

同用名: ECSODPT

基因 ID: 25352 | 基因类型: protein coding

关于 Sod3

功能概要

Enables superoxide dismutase activity. Involved in blood vessel diameter maintenance; response to copper ion; and response to oxidative stress. Located in several cellular components, including collagen-containing extracellular matrix; extracellular space; and nucleus. Used to study hypertension. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3). [provided by Alliance of Genome Resources, Apr 2022]

Sod3 基因产物(1)

mRNA Protein Name
NM_012880.2 NP_037012.1 extracellular superoxide dismutase [Cu-Zn] precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables superoxide dismutase activity IDA
IDA: 通过直接分析推断
8643556 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood vessel diameter maintenance IMP
IMP: 通过突变表型推断
24322611 RGD
involved in response to copper ion IMP
IMP: 通过突变表型推断
16081273 RGD
involved in response to oxidative stress IEP
IEP: 通过表达模式推断
15485085 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
16372329 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
8643556 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

extracellular superoxide dismutase [Cu-Zn]

EC-SOD

Superoxide dimutase 3

extracellular superoxide dismutase

superoxide dismutase 3, extracellular

superoxide dismutase B

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sod3 NCBI NCBI:6649