2. Gene
  3. Aqp2 - aquaporin 2 Gene

Aqp2 - aquaporin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: AQP-2; aquaporin-2

基因 ID: 25386 | 基因类型: protein coding

关于 Aqp2

功能概要

Enables PDZ domain binding activity; actin binding activity; and water transmembrane transporter activity. Involved in several processes, including actin filament depolymerization; cellular response to water deprivation; and response to glucagon. Located in several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and trans-Golgi network. Part of protein-containing complex. Used to study diabetes insipidus. Biomarker of hypertension and nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus. Orthologous to human AQP2 (Aquaporin 2). [provided by Alliance of Genome Resources, Apr 2022]

Aqp2 基因产物(1)

mRNA Protein Name
NM_012909.3 NP_037041.3 aquaporin-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
15196935 RGD
enables actin binding IDA
IDA: 通过直接分析推断
15336526 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
17636261 RGD
enables water transmembrane transporter activity IMP
IMP: 通过突变表型推断
9321919 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin filament depolymerization IDA
IDA: 通过直接分析推断
18678705 RGD
involved in cell volume homeostasis IMP
IMP: 通过突变表型推断
18094031 RGD
involved in cellular response to water deprivation IDA
IDA: 通过直接分析推断
15196935 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
18293204 RGD
involved in hyperosmotic response IEP
IEP: 通过表达模式推断
19138132 RGD
involved in positive regulation of calcium ion transport IMP
IMP: 通过突变表型推断
18094031 RGD
involved in response to calcium ion IEP
IEP: 通过表达模式推断
19138132 RGD
involved in response to glucagon IEP
IEP: 通过表达模式推断
18829741 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
17376764 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
18824919 RGD
involved in response to salt stress IEP
IEP: 通过表达模式推断
12176047 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
15610244 RGD
involved in water transport IEP
IEP: 通过表达模式推断
11518698 RGD
involved in water transport IMP
IMP: 通过突变表型推断
9321919 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
11518698 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
15579502 RGD
located in clathrin-coated vesicle IDA
IDA: 通过直接分析推断
18843259 RGD
located in early endosome IDA
IDA: 通过直接分析推断
18843259 RGD
located in exocytic vesicle IDA
IDA: 通过直接分析推断
15037626 RGD
located in plasma membrane IMP
IMP: 通过突变表型推断
9321919 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15196935 RGD
located in trans-Golgi network IDA
IDA: 通过直接分析推断
15905145 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

aquaporin-2

ADH water channel

AQP-CD

WCH-CD

aquaporin 2 (collecting duct)

aquaporin-CD

collecting duct water channel protein

water channel protein for renal collecting duct

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N2057 Steviol Inhibitor 99.69% 否
HY-RS00874 AQP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17446 Aqp3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18336 Aqp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24815 Aqp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W288951 FMP-API-1 Activator / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aqp2 NCBI NCBI:359
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