2. Gene
  3. BCAN - Bcan brevican Gene

BCAN - Bcan brevican Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: BEHAB; ALPBRE

基因 ID: 25393 | 基因类型: protein coding

关于 BCAN

功能概要

Predicted to enable calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Involved in cell-matrix adhesion; nervous system development; and regulation of neuronal synaptic plasticity. Located in several cellular components, including dendrite; main axon; and perineuronal net. Is anchored component of membrane. Is active in GABA-ergic synapse; glutamatergic synapse; and perisynaptic extracellular matrix. Used to study high grade glioma. Biomarker of high grade glioma and middle cerebral artery infarction. Orthologous to human BCAN (brevican). [provided by Alliance of Genome Resources, Apr 2022]

BCAN 基因产物(2)

mRNA Protein Name
NM_001033665.1 NP_001028837.1 brevican core protein isoform 1 precursor
NM_012916.2 NP_037048.2 brevican core protein isoform 2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell-matrix adhesion IDA
IDA: 通过直接分析推断
11208904 RGD
involved in gliogenesis IEP
IEP: 通过表达模式推断
7869103 RGD
involved in neuron projection extension IDA
IDA: 通过直接分析推断
11208904 RGD
involved in regulation of neuronal synaptic plasticity IEP
IEP: 通过表达模式推断
15935069 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
16503162 RGD
located in axon IDA
IDA: 通过直接分析推断
17709431 RGD
located in axon initial segment IDA
IDA: 通过直接分析推断
17709431 RGD
located in cell surface IDA
IDA: 通过直接分析推断
12799382 RGD
located in dendrite IDA
IDA: 通过直接分析推断
7592978 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
7592978 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
16503162 RGD
located in node of Ranvier IDA
IDA: 通过直接分析推断
17709431 RGD
located in perineuronal net IDA
IDA: 通过直接分析推断
16644727 RGD
is active in perisynaptic extracellular matrix IDA
IDA: 通过直接分析推断
10414531 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
7592978 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

brevican core protein

brain-enriched hyaluronan-binding protein

brevican (brain specific proteoglycan in the aggrecan family)

brevican core protein-like

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS18912 Bcan Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01394 BCAN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25403 Bcan Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens BCAN NCBI NCBI:63827
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