2. Gene
  3. Cacna2d1 - calcium voltage-gated channel auxiliary subunit alpha2delta 1 Gene

Cacna2d1 - calcium voltage-gated channel auxiliary subunit alpha2delta 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CCHLA2; Cacna2; DHSCCA

基因 ID: 25399 | 基因类型: protein coding

关于 Cacna2d1

功能概要

Enables voltage-gated Calcium Channel activity. Involved in calcium ion transport and regulation of ion transmembrane transport. Part of L-type voltage-gated Calcium Channel complex. Is active in glutamatergic synapse. Is anchored component of postsynaptic membrane and anchored component of presynaptic active zone membrane. Orthologous to human CACNA2D1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1). [provided by Alliance of Genome Resources, Apr 2022]

Cacna2d1 基因产物(3)

mRNA Protein Name
NM_001110847.1 NP_001104317.1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 3 precursor
NM_001110848.1 NP_001104318.1 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 2 precursor
NM_012919.3 NP_037051.2 voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19818485 RGD
enables voltage-gated calcium channel activity IMP
IMP: 通过突变表型推断
11604404 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium ion transmembrane transport IDA
IDA: 通过直接分析推断
25527503 RGD
involved in calcium ion transmembrane transport via high voltage-gated calcium channel IDA
IDA: 通过直接分析推断
25527503 RGD
involved in calcium ion transport into cytosol IDA
IDA: 通过直接分析推断
25527503 RGD
involved in positive regulation of voltage-gated calcium channel activity IDA
IDA: 通过直接分析推断
20478999 RGD
involved in regulation of membrane repolarization during action potential IDA
IDA: 通过直接分析推断
25527503 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of L-type voltage-gated calcium channel complex IDA
IDA: 通过直接分析推断
25527503 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
19339603 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
19339603 RGD
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
19339603 RGD
part of voltage-gated calcium channel complex IDA
IDA: 通过直接分析推断
21611731 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

voltage-dependent calcium channel subunit alpha-2/delta-1

Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type)

calcium channel, voltage-dependent, alpha2/delta subunit 1

voltage-gated calcium channel subunit alpha-2/delta-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01801 CACNA2D1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19290 Cacna2d1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25780 Cacna2d1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cacna2d1 NCBI NCBI:781
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