1. Gene
  2. Dpysl3 - dihydropyrimidinase-like 3 Gene

Dpysl3 - dihydropyrimidinase-like 3 Gene

种属: Rattus norvegicus

同用名: Crmp4; TUC-4b

基因 ID: 25418 | 基因类型: protein coding

关于 Dpysl3

功能概要

Enables SH3 domain binding activity; chondroitin sulfate binding activity; and identical protein binding activity. Involved in several processes, including actin filament organization; regulation of plasma membrane bounded cell projection organization; and response to axon injury. Located in several cellular components, including cell body; growth cone; and lamellipodium. Part of filamentous actin. Is active in synapse. Colocalizes with exocytic vesicle. Orthologous to human DPYSL3 (dihydropyrimidinase like 3). [provided by Alliance of Genome Resources, Apr 2022]

Dpysl3 基因产物(2)

mRNA Protein Name
NM_001398556.1 NP_001385485.1 dihydropyrimidinase-related protein 3 isoform 2
NM_012934.2 NP_037066.1 dihydropyrimidinase-related protein 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH3 domain binding IDA
IDA: 通过直接分析推断
12684468 RGD
enables chondroitin sulfate binding IDA
IDA: 通过直接分析推断
12444086 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
16181627 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin crosslink formation IDA
IDA: 通过直接分析推断
16181627 RGD
involved in actin filament bundle assembly IDA
IDA: 通过直接分析推断
16181627 RGD
involved in cellular response to cytokine stimulus IEP
IEP: 通过表达模式推断
20800647 RGD
involved in negative regulation of cell migration IMP
IMP: 通过突变表型推断
16181627 RGD
involved in negative regulation of neuron projection development IMP
IMP: 通过突变表型推断
17301178 RGD
involved in neuron development IEP
IEP: 通过表达模式推断
8815901 RGD
involved in positive regulation of filopodium assembly IDA
IDA: 通过直接分析推断
17301178 RGD
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
12684468 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
20800647 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell body IDA
IDA: 通过直接分析推断
16181627 RGD
located in cytosol IDA
IDA: 通过直接分析推断
16181627 RGD
located in exocytic vesicle IDA
IDA: 通过直接分析推断
12684468 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
12444086 RGD
part of filamentous actin IDA
IDA: 通过直接分析推断
16181627 RGD
located in growth cone IDA
IDA: 通过直接分析推断
12684468 RGD
located in lamellipodium IDA
IDA: 通过直接分析推断
16181627 RGD
is active in synapse EXP
EXP: 通过实验结果推断
15169875 RGD
is active in synapse IDA
IDA: 通过直接分析推断
15169875 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dihydropyrimidinase-related protein 3

CRMP-4

DRP-3

TOAD-64/Ulip/CRMP protein 4b

collapsin response mediator protein 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dpysl3 NCBI NCBI:1809