Lamb2 - laminin subunit beta 2 Gene

种属: Rattus norvegicus

同用名: SLAM

关于 Lamb2

功能概要

Predicted to enable Integrin binding activity. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within several processes, including metanephric glomerulus development; neurogenesis; and visual perception. Predicted to be located in basement membrane and neuromuscular junction. Predicted to be part of laminin-3 complex. Predicted to be active in synaptic cleft. Used to study proteinuria. Human ortholog(s) of this gene implicated in Pierson syndrome and nephrotic syndrome type 5. Orthologous to human LAMB2 (laminin subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]