2. Gene
  3. Alpl - alkaline phosphatase, biomineralization associated Gene

Alpl - alkaline phosphatase, biomineralization associated Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Akp2; PHOA; TNAP

基因 ID: 25586 | 基因类型: protein coding

关于 Alpl

功能概要

Enables Alkaline Phosphatase activity. Involved in cementum mineralization; response to glucocorticoid; and response to lipopolysaccharide. Located in extracellular space and plasma membrane. Is active in extracellular membrane-bounded organelle. Biomarker of uremia. Human ortholog(s) of this gene implicated in adult hypophosphatasia; childhood hypophosphatasia; hypophosphatasia; and infantile hypophosphatasia. Orthologous to human ALPL (Alkaline Phosphatase, biomineralization associated). [provided by Alliance of Genome Resources, Apr 2022]

Alpl 基因产物(1)

mRNA Protein Name
NM_013059.2 NP_037191.2 alkaline phosphatase, tissue-nonspecific isozyme precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alkaline phosphatase activity IDA
IDA: 通过直接分析推断
3472490 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cementum mineralization IEP
IEP: 通过表达模式推断
17043865 RGD
involved in response to glucocorticoid IDA
IDA: 通过直接分析推断
2039500 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
20818503 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
11810315 RGD
involved in response to macrophage colony-stimulating factor IEP
IEP: 通过表达模式推断
7669437 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
20818503 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
32710882 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
19697513 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alkaline phosphatase, tissue-nonspecific isozyme

AP-TNAP

TNSALP

Tissue-nonspecific ALP alkaline phosphatase

alkaline phosphatase 2, liver

alkaline phosphatase liver/bone/kidney isozyme

alkaline phosphatase, liver/bone/kidney

phosphoamidase

phosphocreatine phosphatase

tissue-nonspecific alkaline

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00632 ALPL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17484 Alpl Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23942 Alpl Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alpl NCBI NCBI:249
Mus musculus Alpl NCBI NCBI:11647
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