2. Gene
  3. Otc - ornithine transcarbamylase Gene

Otc - ornithine transcarbamylase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25611 | 基因类型: protein coding

关于 Otc

功能概要

Enables several functions, including identical protein binding activity; ornithine carbamoyltransferase activity; and phosphate ion binding activity. Involved in several processes, including alpha-amino acid metabolic process; response to biotin; and urea cycle. Located in mitochondrial inner membrane. Used to study ornithine carbamoyltransferase deficiency. Biomarker of cholestasis; fatty liver disease; and obesity. Human ortholog(s) of this gene implicated in ornithine carbamoyltransferase deficiency. Orthologous to human OTC (ornithine transcarbamylase). [provided by Alliance of Genome Resources, Apr 2022]

Otc 基因产物(1)

mRNA Protein Name
NM_013078.2 NP_037210.1 ornithine transcarbamylase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amino acid binding IMP
IMP: 通过突变表型推断
2290837 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
2290837 RGD
enables ornithine carbamoyltransferase activity IDA
IDA: 通过直接分析推断
3680220 RGD
enables ornithine carbamoyltransferase activity IMP
IMP: 通过突变表型推断
2290837 RGD
enables phosphate ion binding IMP
IMP: 通过突变表型推断
2290837 RGD
enables phospholipid binding IDA
IDA: 通过直接分析推断
3680220 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in citrulline biosynthetic process IDA
IDA: 通过直接分析推断
9472964 RGD
involved in liver development IEP
IEP: 通过表达模式推断
8690412 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
9544996 RGD
involved in monoatomic anion homeostasis IDA
IDA: 通过直接分析推断
4062872 RGD
involved in ornithine metabolic process IDA
IDA: 通过直接分析推断
4062872 RGD
involved in response to biotin IEP
IEP: 通过表达模式推断
8558326 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
9628242 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
9628242 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
14625847 RGD
involved in response to zinc ion IEP
IEP: 通过表达模式推断
11686784 RGD
involved in urea cycle IDA
IDA: 通过直接分析推断
3680220 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
3680220 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ornithine transcarbamylase, mitochondrial

OTCase

ornithine carbamoyltransferase, mitochondrial

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125947 4-Epioxytetracycline 99.16% 否
HY-RS09859 OTC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17937 Otc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24408 Otc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Otc NCBI NCBI:5009
Mus musculus Otc NCBI NCBI:18416
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