1. Gene
  2. Crem - cAMP responsive element modulator Gene

Crem - cAMP responsive element modulator Gene

种属: Rattus norvegicus

同用名: Icer

基因 ID: 25620 | 基因类型: protein coding

关于 Crem

功能概要

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including glucose metabolic process; regulation of circadian rhythm; and retinoic acid receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ATF4-CREB1 transcription factor complex. Biomarker of transient cerebral ischemia. Orthologous to human CREM (cAMP responsive element modulator). [provided by Alliance of Genome Resources, Apr 2022]

Crem 基因产物(8)

mRNA Protein Name
NM_001110860.2 NP_001104330.1 cAMP-responsive element modulator isoform 3
NM_001271101.1 NP_001258030.1 cAMP-responsive element modulator isoform 4
NM_001271102.1 NP_001258031.1 cAMP-responsive element modulator isoform 5
NM_001271245.1 NP_001258174.1 cAMP-responsive element modulator isoform 6
NM_001271246.1 NP_001258175.1 cAMP-responsive element modulator isoform 7
NM_001271247.1 NP_001258176.1 cAMP-responsive element modulator isoform 8
NM_001271248.1 NP_001258177.1 cAMP-responsive element modulator isoform 9
NM_017334.2 NP_059030.2 cAMP-responsive element modulator isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fatty acid metabolic process IEP
IEP: 通过表达模式推断
14534319 RGD
involved in glucose metabolic process IEP
IEP: 通过表达模式推断
14534319 RGD
involved in retinoic acid receptor signaling pathway IEP
IEP: 通过表达模式推断
15725648 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cAMP-responsive element modulator

CRE modulator

cAMP responsive element moderator

inducible cyclic AMP early repressor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Crem NCBI NCBI:1390