1. Gene
  2. Cma1 - chymase 1 Gene

Cma1 - chymase 1 Gene

种属: Rattus norvegicus

同用名: MCP3P; Mcpt5

基因 ID: 25627 | 基因类型: protein coding

关于 Cma1

功能概要

Enables peptide binding activity and serine-type endopeptidase activity. Involved in several processes, including cellular response to glucose stimulus; midbrain development; and positive regulation of angiogenesis. Located in extracellular region. Human ortholog(s) of this gene implicated in asthma; atopic dermatitis; hypertrophic cardiomyopathy; and sarcoidosis. Orthologous to human CMA1 (chymase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cma1 基因产物(1)

mRNA Protein Name
NM_013092.2 NP_037224.1 chymase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptide binding IMP
IMP: 通过突变表型推断
15869764 RGD
enables serine-type endopeptidase activity IDA
IDA: 通过直接分析推断
12444981 RGD
enables serine-type endopeptidase activity IMP
IMP: 通过突变表型推断
15869764 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
17483239 RGD
involved in midbrain development IEP
IEP: 通过表达模式推断
21396433 RGD
involved in peptide metabolic process IEP
IEP: 通过表达模式推断
15265236 RGD
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
15723097 RGD
involved in protein catabolic process IDA
IDA: 通过直接分析推断
12900423 RGD
involved in protein processing IDA
IDA: 通过直接分析推断
15869764 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
15265236 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

chymase

alpha-chymase

chymase 1, mast cell

mast cell protease 3

mast cell protease 5

mast cell protease III

rMCP-3

rMCP-5

rMCP-III

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cma1 NCBI NCBI:1215
Mus musculus Cma1 NCBI NCBI:17228