1. Gene
  2. Fkbp1a - FKBP prolyl isomerase 1A Gene

Fkbp1a - FKBP prolyl isomerase 1A Gene

种属: Rattus norvegicus

同用名: Fkbp2; FKBP12

基因 ID: 25639 | 基因类型: protein coding

关于 Fkbp1a

功能概要

Enables several functions, including FK506 binding activity; HSP70 protein binding activity; and type I transforming growth factor beta receptor binding activity. Involved in response to iron ion. Located in axon terminus and intracellular membrane-bounded organelle. Biomarker of Parkinsonism. Orthologous to several human genes including FKBP1A (FKBP prolyl isomerase 1A). [provided by Alliance of Genome Resources, Apr 2022]

Fkbp1a 基因产物(1)

mRNA Protein Name
NM_013102.3 NP_037234.2 peptidyl-prolyl cis-trans isomerase FKBP1A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables FK506 binding IDA
IDA: 通过直接分析推断
9013543 RGD
enables Hsp70 protein binding IPI
IPI: 通过物理相互作用推断
17877381 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
17877381 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
17877381 RGD
enables transforming growth factor beta receptor binding IDA
IDA: 通过直接分析推断
7518616 RGD
enables type I transforming growth factor beta receptor binding IDA
IDA: 通过直接分析推断
7518616 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to iron ion IEP
IEP: 通过表达模式推断
17546681 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
12494287 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase FKBP1A

12 kDa FK506-binding protein

12 kDa FKBP

FK506 binding protein 1a

FK506 binding protein 2 (13 kDa)

FK506-binding protein 1 (12kD)

FK506-binding protein 1A

FKBP-12

FKBP-1A

PPIase FKBP1A

immunophilin FKBP12

rotamase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fkbp1a NCBI NCBI:2280
Mus musculus Fkbp1a NCBI NCBI:14225