2. Gene
  3. Igfbp2 - insulin-like growth factor binding protein 2 Gene

Igfbp2 - insulin-like growth factor binding protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: IBP-2; BRL-BP; IGFBP-2; ILGFBPA

基因 ID: 25662 | 基因类型: protein coding

关于 Igfbp2

功能概要

Enables insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Involved in several processes, including response to estradiol; response to estrogen; and response to retinoic acid. Located in apical plasma membrane; cytoplasmic vesicle; and extracellular space. Biomarker of hypertension and hypothyroidism. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP2 (Insulin like growth factor binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Igfbp2 基因产物(1)

mRNA Protein Name
NM_013122.2 NP_037254.2 insulin-like growth factor-binding protein 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables insulin-like growth factor I binding IDA
IDA: 通过直接分析推断
2538475 RGD
enables insulin-like growth factor I binding IMP
IMP: 通过突变表型推断
2538475 RGD
enables insulin-like growth factor II binding IDA
IDA: 通过直接分析推断
1709938 RGD
enables insulin-like growth factor II binding IPI
IPI: 通过物理相互作用推断
2538475 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
16720626 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
17123939 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
10842239 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
12801995 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
15705658 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
17308996 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
15576465 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
7536658 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
11880314 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
10842239 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
15613074 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
10842239 RGD
located in extracellular region IDA
IDA: 通过直接分析推断
2426267 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
2538475 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

insulin-like growth factor-binding protein 2

IGF-binding protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06625 IGFBP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16821 Igfbp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23261 Igfbp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991042 Anti-IGFBP2 Antibody (M14) Antagonist ≥99.0% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Igfbp2 NCBI NCBI:3485
Macaca fascicularis Igfbp2 NCBI NCBI:102131255
Mus musculus Igfbp2 NCBI NCBI:16008
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