1. Gene
  2. Ass1 - argininosuccinate synthase 1 Gene

Ass1 - argininosuccinate synthase 1 Gene

种属: Rattus norvegicus

同用名: Ass; ASSA

基因 ID: 25698 | 基因类型: protein coding

关于 Ass1

功能概要

Enables argininosuccinate synthase activity and toxic substance binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipid; and cellular response to organonitrogen compound. Located in several cellular components, including cell body fiber; mitochondrial outer membrane; and perikaryon. Biomarker of uveitis. Human ortholog(s) of this gene implicated in citrullinemia; classic citrullinemia; hepatocellular carcinoma; and melanoma. Orthologous to human ASS1 (argininosuccinate synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ass1 基因产物(1)

mRNA Protein Name
NM_013157.4 NP_037289.1 argininosuccinate synthase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables argininosuccinate synthase activity IDA
IDA: 通过直接分析推断
4062872 RGD
enables argininosuccinate synthase activity IMP
IMP: 通过突变表型推断
19491403 RGD
enables toxic substance binding IPI
IPI: 通过物理相互作用推断
11083085 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-arginine biosynthetic process IDA
IDA: 通过直接分析推断
12470967 RGD
involved in L-arginine biosynthetic process IMP
IMP: 通过突变表型推断
19491403 RGD
involved in acute-phase response IEP
IEP: 通过表达模式推断
15698416 RGD
involved in argininosuccinate metabolic process IDA
IDA: 通过直接分析推断
4062872 RGD
involved in cellular response to amine stimulus IEP
IEP: 通过表达模式推断
18457831 RGD
involved in cellular response to amino acid stimulus IEP
IEP: 通过表达模式推断
9893939 RGD
involved in cellular response to ammonium ion IEP
IEP: 通过表达模式推断
10353334 RGD
involved in cellular response to cAMP IEP
IEP: 通过表达模式推断
8923475 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
9395312 RGD
involved in cellular response to glucagon stimulus IEP
IEP: 通过表达模式推断
9395312 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
9879717 RGD
involved in cellular response to oleic acid IEP
IEP: 通过表达模式推断
8985169 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
11072090 RGD
involved in cellular response to type II interferon IEP
IEP: 通过表达模式推断
11072090 RGD
involved in diaphragm development IEP
IEP: 通过表达模式推断
9618389 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
10473900 RGD
involved in liver development IEP
IEP: 通过表达模式推断
9395312 RGD
involved in midgut development IEP
IEP: 通过表达模式推断
9544996 RGD
involved in response to amine IEP
IEP: 通过表达模式推断
16168957 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
17938381 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
16339744 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
19651254 RGD
involved in response to glucocorticoid IDA
IDA: 通过直接分析推断
8923475 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
9688877 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
12589771 RGD
involved in response to mycotoxin IDA
IDA: 通过直接分析推断
11083085 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
15257170 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
9688877 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
9688877 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
20452409 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
9252090 RGD
involved in response to zinc ion IDA
IDA: 通过直接分析推断
11686784 RGD
involved in urea cycle IDA
IDA: 通过直接分析推断
4062872 RGD
involved in urea cycle IMP
IMP: 通过突变表型推断
19491403 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell body fiber IDA
IDA: 通过直接分析推断
12445581 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
8867809 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12445581 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
17900569 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

argininosuccinate synthase

argininosuccinate synthetase 1

arginosuccinate synthetase 1

citrulline--aspartate ligase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ass1 NCBI NCBI:445