1. Gene
  2. Il2ra - interleukin 2 receptor subunit alpha Gene

Il2ra - interleukin 2 receptor subunit alpha Gene

种属: Rattus norvegicus

同用名: IL2RAC

基因 ID: 25704 | 基因类型: protein coding

关于 Il2ra

功能概要

Enables interleukin-2 receptor activity. Involved in inflammatory response to antigenic stimulus; positive regulation of T cell differentiation; and positive regulation of T cell proliferation. Located in cell surface. Used to study Korean hemorrhagic fever; asthma; and diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il2ra 基因产物(1)

mRNA Protein Name
NM_013163.2 NP_037295.1 interleukin-2 receptor subunit alpha precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-2 receptor activity IPI
IPI: 通过物理相互作用推断
2592769 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in inflammatory response to antigenic stimulus IMP
IMP: 通过突变表型推断
10389888 RGD
involved in positive regulation of T cell differentiation IMP
IMP: 通过突变表型推断
9352365 RGD
involved in positive regulation of T cell proliferation IMP
IMP: 通过突变表型推断
9352365 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
10210776 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interleukin-2 receptor subunit alpha

IL-2 receptor alpha subunit

IL-2 receptor subunit alpha

IL-2-RA

IL-2R subunit alpha

IL2-RA

interleukin 2 receptor, alpha chain

重组 Il2ra 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74809 IL-2R alpha/CD25 Protein, Rat (sf9, His) P26897/NP_037295.1 (E22-Q235) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il2ra NCBI NCBI:3559
Canis familiaris Il2ra NCBI NCBI:403870
Macaca fascicularis Il2ra NCBI NCBI:102123605
Mus musculus Il2ra NCBI NCBI:16184