2. Gene
  3. Tgfb3 - transforming growth factor, beta 3 Gene

Tgfb3 - transforming growth factor, beta 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: TGF-B3

基因 ID: 25717 | 基因类型: protein coding

关于 Tgfb3

功能概要

Predicted to enable several functions, including cytokine activity; transforming growth factor beta binding activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including regulation of signal transduction; response to estrogen; and skeletal system morphogenesis. Located in several cellular components, including T-tubule; neuronal cell body; and secretory granule. Biomarker of diabetic neuropathy. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 5; arrhythmogenic right ventricular cardiomyopathy; and arrhythmogenic right ventricular dysplasia 1. Orthologous to human TGFB3 (transforming growth factor beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Tgfb3 基因产物(1)

mRNA Protein Name
NM_013174.2 NP_037306.1 transforming growth factor beta-3 proprotein preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
18406405 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in digestive tract development IEP
IEP: 通过表达模式推断
12815632 RGD
involved in embryonic neurocranium morphogenesis IDA
IDA: 通过直接分析推断
11002343 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
15927076 RGD
involved in frontal suture morphogenesis IEP
IEP: 通过表达模式推断
12416537 RGD
involved in inner ear development IEP
IEP: 通过表达模式推断
16479080 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11002343 RGD
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
12071374 RGD
involved in positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
14605008 RGD
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
11002343 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
16532270 RGD
involved in response to estrogen IDA
IDA: 通过直接分析推断
14605008 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
14697406 RGD
involved in response to laminar fluid shear stress IEP
IEP: 通过表达模式推断
16217485 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
9281452 RGD
located in cell surface IDA
IDA: 通过直接分析推断
16479080 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
16891311 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15214860 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
15214860 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transforming growth factor beta-3 proprotein

TGF-beta-3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14442 TGFB3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16996 Tgfb3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23439 Tgfb3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tgfb3 NCBI NCBI:7043
Mus musculus Tgfb3 NCBI NCBI:21809
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