2. Gene
  3. Got2 - glutamic-oxaloacetic transaminase 2 Gene

Got2 - glutamic-oxaloacetic transaminase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: mAAT; ASPATA

基因 ID: 25721 | 基因类型: protein coding

关于 Got2

功能概要

Enables several functions, including L-aspartate:2-oxoglutarate aminotransferase activity; anion binding activity; and identical protein binding activity. Involved in several processes, including dicarboxylic acid metabolic process; lactation; and response to morphine. Located in several cellular components, including T-tubule; mitochondrial inner membrane; and perikaryon. Part of protein-containing complex. Biomarker of acute kidney failure; neurodegenerative disease; obesity; and schizophrenia. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 82. Orthologous to human GOT2 (glutamic-oxaloacetic transaminase 2). [provided by Alliance of Genome Resources, Apr 2022]

Got2 基因产物(1)

mRNA Protein Name
NM_013177.2 NP_037309.1 aspartate aminotransferase, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-aspartate:2-oxoglutarate aminotransferase activity IDA
IDA: 通过直接分析推断
10395949 RGD
enables L-aspartate:2-oxoglutarate aminotransferase activity IMP
IMP: 通过突变表型推断
12686151 RGD
enables amino acid binding IDA
IDA: 通过直接分析推断
14522984 RGD
enables carboxylic acid binding IDA
IDA: 通过直接分析推断
14522984 RGD
enables enzyme binding IDA
IDA: 通过直接分析推断
3997814 RGD
enables identical protein binding IMP
IMP: 通过突变表型推断
12686151 RGD
enables phospholipid binding IDA
IDA: 通过直接分析推断
3997814 RGD
enables pyridoxal phosphate binding IDA
IDA: 通过直接分析推断
14522984 RGD
enables pyridoxal phosphate binding IMP
IMP: 通过突变表型推断
12686151 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in L-glutamate biosynthetic process IDA
IDA: 通过直接分析推断
16489927 RGD
involved in amino acid metabolic process IDA
IDA: 通过直接分析推断
14522984 RGD
involved in aspartate metabolic process IMP
IMP: 通过突变表型推断
12686151 RGD
involved in dicarboxylic acid metabolic process IDA
IDA: 通过直接分析推断
14522984 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
27317891 RGD
involved in lactation IEP
IEP: 通过表达模式推断
28798692 RGD
involved in oxaloacetate metabolic process IDA
IDA: 通过直接分析推断
16489927 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
23743348 RGD
involved in response to muscle activity IEP
IEP: 通过表达模式推断
22028411 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
23743348 RGD
located in cell surface IDA
IDA: 通过直接分析推断
11962739 RGD
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
3997814 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
7838383 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
3997814 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
23743348 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

aspartate aminotransferase, mitochondrial

FABP-1

FABPpm

Glutamate oxaloacetate transaminase 2, mitochondrial (aspartate aminotransferase 2)

fatty acid-binding protein

glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

kynurenine aminotransferase 4

kynurenine a

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05606 GOT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17809 Got2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24277 Got2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Got2 NCBI NCBI:2806
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