2. Gene
  3. Hcrt - hypocretin neuropeptide precursor Gene

Hcrt - hypocretin neuropeptide precursor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: orexin-A

基因 ID: 25723 | 基因类型: protein coding

关于 Hcrt

功能概要

Enables neuropeptide hormone activity; type 1 hypocretin receptor binding activity; and type 2 hypocretin receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of metal ion transport; and regulation of transmission of nerve impulse. Located in secretory granule. Biomarker of hyperglycemia and obesity. Human ortholog(s) of this gene implicated in narcolepsy. Orthologous to human HCRT (hypocretin neuropeptide precursor). [provided by Alliance of Genome Resources, Apr 2022]

Hcrt 基因产物(1)

mRNA Protein Name
NM_013179.3 NP_037311.1 hypocretin neuropeptide precursor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables neuropeptide hormone activity IDA
IDA: 通过直接分析推断
16247802 RGD
enables type 1 orexin receptor binding IDA
IDA: 通过直接分析推断
12890892 RGD
enables type 2 orexin receptor binding IDA
IDA: 通过直接分析推断
12890892 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in eating behavior IDA
IDA: 通过直接分析推断
15961555 RGD
involved in excitatory postsynaptic potential IDA
IDA: 通过直接分析推断
16247802 RGD
involved in negative regulation of DNA replication IDA
IDA: 通过直接分析推断
16141395 RGD
involved in negative regulation of potassium ion transport IDA
IDA: 通过直接分析推断
16247802 RGD
involved in negative regulation of transmission of nerve impulse IDA
IDA: 通过直接分析推断
15746258 RGD
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
16247802 RGD
involved in positive regulation of calcium ion transport IMP
IMP: 通过突变表型推断
15858425 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
15858425 RGD
involved in positive regulation of transmission of nerve impulse IDA
IDA: 通过直接分析推断
15746258 RGD
involved in regulation of neurotransmitter secretion IDA
IDA: 通过直接分析推断
15664710 RGD
NOT involved in release of sequestered calcium ion into cytosol IMP
IMP: 通过突变表型推断
15858425 RGD
involved in response to alcohol IEP
IEP: 通过表达模式推断
32619610 RGD
involved in temperature homeostasis IDA
IDA: 通过直接分析推断
15479129 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in neuronal dense core vesicle lumen IDA
IDA: 通过直接分析推断
9419374 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
9419374 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hypocretin neuropeptide precursor

Hypocretin (orexin) neuropeptide

orexin

prepro-orexin

preprohypocretin

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-128850 N-Acetyl-D-mannosamine 99.99% Phase 2
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06050 HCRT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18943 Hcrt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25433 Hcrt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hcrt NCBI NCBI:3060
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