2. Gene
  3. Alas2 - 5'-aminolevulinate synthase 2 Gene

Alas2 - 5'-aminolevulinate synthase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25748 | 基因类型: protein coding

关于 Alas2

功能概要

Enables 5-aminolevulinate synthase activity and coenzyme A binding activity. Involved in several processes, including gland development; response to benzene; and response to lead ion. Located in mitochondrion. Biomarker of anemia; bilirubin metabolic disorder; and hemolytic anemia. Human ortholog(s) of this gene implicated in cutaneous porphyria; erythropoietic protoporphyria; hemochromatosis; sideroblastic anemia; and sideroblastic anemia 1. Orthologous to human ALAS2 (5'-aminolevulinate synthase 2). [provided by Alliance of Genome Resources, Apr 2022]

Alas2 基因产物(1)

mRNA Protein Name
NM_013197.1 NP_037329.1 5-aminolevulinate synthase, erythroid-specific, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 5-aminolevulinate synthase activity IDA
IDA: 通过直接分析推断
8407861 RGD
enables coenzyme A binding IDA
IDA: 通过直接分析推断
8407861 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in lactation IEP
IEP: 通过表达模式推断
18255020 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
6895999 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
18255020 RGD
involved in response to benzene IEP
IEP: 通过表达模式推断
6895089 RGD
involved in response to cobalt ion IEP
IEP: 通过表达模式推断
2781150 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
21737922 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
17095594 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
16597373 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16005536 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5-aminolevulinate synthase, erythroid-specific, mitochondrial

5-aminolevulinic acid synthase 2

ALAS-E

Aminolevulinate synthase 2, delta

aminolevulinate, delta-, synthase 2

aminolevulinic acid synthase 2, erythroid

aminolevulinic acid synthase 2, erythroid-like

delta-ALA synthase 2

delta-ALA synthetase

delta-

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00555 ALAS2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19407 Alas2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25899 Alas2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alas2 NCBI NCBI:212
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