1. Gene
  2. TRIM58 - tripartite motif containing 58 Gene

TRIM58 - tripartite motif containing 58 Gene

中文名称:含三方基序 58

种属: Homo sapiens

同用名: BIA2

基因 ID: 25893 | 基因类型: protein coding

关于 TRIM58

This gene has 1 transcript (splice variant), 92 orthologues and 80 paralogues. Biased expression in bone marrow (RPKM 12.4), thyroid (RPKM 11.2) and 5 other tissues.

功能概要

预测启用动力蛋白重链结合活性;动力蛋白中间链结合活性;和泛素蛋白连接酶活性。预计参与多个过程,包括红细胞去核的正调控;蛋白质泛素化;和调节沿微管的核迁移。预计在细胞质中有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM58 基因产物(1)

mRNA Protein Name
NM_015431.4 NP_056246.3 E3 ubiquitin-protein ligase TRIM58

TRIM58 蛋白结构

zf-C3HC4_4

zf-C3HC4_4: zinc finger of C3HC4-type, RING (16 - 60)

zf-B_box

zf-B_box: B-box zinc finger (93 - 132)

PRY

PRY: SPRY-associated domain (293 - 341)

SPRY

SPRY: SPRY domain (343 - 450)

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  • 486 a.a.
蛋白主名 其他名称

E3 ubiquitin-protein ligase TRIM58

RING-type E3 ubiquitin transferase TRIM58

直系同源

种属 基因名 来源 基因 ID
Mus musculus TRIM58 MGD MGI:2684862
Canis familiaris TRIM58 VGNC VGNC:47828
Macaca mulatta TRIM58 VGNC VGNC:100177
Rattus norvegicus TRIM58 RGD RGD:1566174
Bos taurus TRIM58 VGNC VGNC:36343
Felis catus TRIM58 VGNC VGNC:66546