ADGRG1 - Adgrg1 adhesion G protein-coupled receptor G1 Gene

种属: Rattus norvegicus

同用名: Gpr56

关于 ADGRG1

功能概要

Predicted to enable several functions, including Collagen binding activity; extracellular matrix binding activity; and heparin binding activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of Rho protein signal transduction; and seminiferous tubule development. Predicted to act upstream of or within cerebral cortex regionalization; hematopoietic stem cell homeostasis; and positive regulation of neural precursor cell proliferation. Predicted to be located in glial limiting end-foot. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in bilateral frontoparietal polymicrogyria and bilateral perisylvian polymicrogyria. Orthologous to human ADGRG1 (adhesion G protein-coupled receptor G1). [provided by Alliance of Genome Resources, Apr 2022]