2. Gene
  3. LRRC32 - leucine rich repeat containing 32 Gene

LRRC32 - leucine rich repeat containing 32 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含富含亮氨酸的重复序列 32

种属: Homo sapiens

同用名: GARP; CPPRDD; D11S833E

基因 ID: 2615 | 基因类型: protein coding

关于 LRRC32

Cytogenetic location: 11q13.5 Genomic coordinates (GRCh38): 11:76,657,524-76,670,747 (from NCBI)

This gene has 5 transcripts (splice variants), 87 orthologues, 22 paralogues and is associated with 1 phenotype. Broad expression in placenta (RPKM 24.7), lung (RPKM 19.4) and 23 other tissues.

功能概要

该基因编码一种 I 型膜蛋白，其中包含 20 个富含亮氨酸的重复序列。染色体区域 11q13-11q14 的改变涉及多种病理学。[RefSeq 提供，2008 年 7 月]

This gene encodes a type I membrane protein which contains 20 leucine-rich repeats. Alterations in the chromosomal region 11q13-11q14 are involved in several pathologies. [provided by RefSeq, Jul 2008]

LRRC32 基因产物(7)

mRNA Protein Name
NM_001128922.2 NP_001122394.1 transforming growth factor beta activator LRRC32 isoform a precursor
NM_001370187.1 NP_001357116.1 transforming growth factor beta activator LRRC32 isoform a precursor
NM_001370188.1 NP_001357117.1 transforming growth factor beta activator LRRC32 isoform a precursor
NM_001370189.1 NP_001357118.1 transforming growth factor beta activator LRRC32 isoform b
NM_001370190.1 NP_001357119.1 transforming growth factor beta activator LRRC32 isoform c
NM_001370191.1 NP_001357120.1 transforming growth factor beta activator LRRC32 isoform d precursor
NM_005512.3 NP_005503.1 transforming growth factor beta activator LRRC32 isoform a precursor

LRRC32 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (22 - 48)

LRR_8

LRR_8: Leucine rich repeat (52 - 109)

LRR_8

LRR_8: Leucine rich repeat (149 - 209)

(219 - 231)

LRR_1

LRR_1: Leucine Rich Repeat (317 - 338)

LRR_8

LRR_8: Leucine rich repeat (365 - 421)

LRR_8

LRR_8: Leucine rich repeat (516 - 573)

  • 0
  • 200
  • 400
  • 600
  • 662 a.a.
蛋白主名 其他名称

transforming growth factor beta activator LRRC32

garpin

重组 LRRC32 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70419 LRRC32 Protein, Human (HEK293, Fc) Q14392 (H20-N627) ≥95%
HY-P72636 GARP&Latent TGF Beta-1 Complex Protein, Human (HEK293, His, Strep) P01137&Q14392 (L30-S390&H20-N627) ≥95%
HY-P77671 GARP (Y137H)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) Q14392 (H20-L628, Y137H)&P01137 (L30-S390) ≥95%
HY-P77672 GARP (S138G)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) Q14392 (H20-L628, S138G)&P01137 (L30-S390) ≥95%
HY-P77673 GARP (G139N)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) Q14392 (H20-L628, G139N)&P01137 (L30-S390) ≥95%
HY-P77674 GARP&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) Q14392 (H20-L628)&P01137 (L30-S390) ≥95%
HY-P77675 GARP&Latent TGF beta Complex Protein, Human (Biotinylated, HEK293, His-Avi) Q14392 (H20-L628,GARP)&P01137 (L30-S390,Latent TGF bata 1) ≥95%
HY-P77676 GARP (Mutated)&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) Q14392 (H20-L628, Y137H, S138G, G139N)&P01137 (L30 ≥95%

关联疾病

疾病名称 别名
Cleft Palate, Proliferative Retinopathy, And Developmental Delay

CPPRDD
Vitreoretinal Degeneration
Vitreoretinopathy
Cleft Palate, Isolated

Cleft Palate

Isolated Cleft Palate

CPI

Cp

Palatoschisis

Cleft Palate Isolated

Uranostaphyloschisis

Congenital Fissure Of Palate

Cleft Of Secondary Palate
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99708 Livmoniplimab Inhibitor 99.25% Phase 3
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07815 LRRC32 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus LRRC32 VGNC VGNC:63294
Macaca mulatta LRRC32 VGNC VGNC:101300
Canis familiaris LRRC32 VGNC VGNC:59054
Bos taurus LRRC32 VGNC VGNC:54884
Rattus norvegicus LRRC32 RGD RGD:1309087
Mus musculus LRRC32 MGD MGI:93882
Macaca fascicularis LRRC32 NCBI
Others LRRC32 NCBI
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