1. Gene
  2. mt-Nd2 - NADH dehydrogenase 2, mitochondrial Gene

mt-Nd2 - NADH dehydrogenase 2, mitochondrial Gene

种属: Rattus norvegicus (strain: BN/SsNHsdMCW)

同用名: ND2

基因 ID: 26194 | 基因类型: protein coding

关于 mt-Nd2

功能概要

Enables ionotropic glutamate receptor binding activity and protein kinase binding activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within Reactive Oxygen Species metabolic process. Located in mitochondrion and postsynaptic density. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder Cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd2 基因产物(2)

mRNA Protein Name
YP_665630.1 NADH dehydrogenase subunit 2 (mitochondrion) [Rattus norvegicus]
YP_665630.1 NADH dehydrogenase subunit 2 (mitochondrion) [Rattus norvegicus]
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
15069201 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
15069201 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to hypoxia IEP
IEP: 通过表达模式推断
33310031 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

NADH dehydrogenase subunit 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens mt-Nd2 NCBI NCBI:4536