2. Gene
  3. ARL5A - ADP ribosylation factor like GTPase 5A Gene

ARL5A - ADP ribosylation factor like GTPase 5A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ADP 核糖基化因子样 GTPase 5A

种属: Homo sapiens

同用名: ARL5; ARFLP5

基因 ID: 26225 | 基因类型: protein coding

关于 ARL5A

Cytogenetic location: 2q23.3 Genomic coordinates (GRCh38): 2:151,798,797-151,828,421 (from NCBI)

This gene has 7 transcripts (splice variants), 212 orthologues and 30 paralogues. Ubiquitous expression in thyroid (RPKM 27.2), heart (RPKM 19.5) and 25 other tissues.

功能概要

该基因编码的蛋白质属于 GTP 结合蛋白的 ARF 家族。凭借其独特的核/核仁定位和与 HP1alpha 的相互作用，该蛋白质在发育过程中受到调节，可能在胚胎发育过程中的核动力学和/或信号级联中发挥作用。可变剪接导致编码不同异构体的多个转录变体。这个基因有多个假基因。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. With its distinctive nuclear/nucleolar localization and interaction with HP1alpha, the protein is developmentally regulated and may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

ARL5A 基因产物(3)

mRNA Protein Name
NM_001037174.2 NP_001032251.1 ADP-ribosylation factor-like protein 5A isoform 2
NM_012097.4 NP_036229.1 ADP-ribosylation factor-like protein 5A isoform 1
NM_177985.3 NP_817114.2 ADP-ribosylation factor-like protein 5A isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein localization to Golgi membrane IGI
IGI: 通过遗传相互作用推断
25795912 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ARL5A 蛋白结构

Arf

Arf: ADP-ribosylation factor family (12 - 174)

  • 0
  • 100
  • 179 a.a.
蛋白主名 其他名称

ADP-ribosylation factor-like protein 5A

ADP-ribosylation factor-like 5

关联疾病

疾病名称 别名
Mucinous Stomach Adenocarcinoma

Mucinous Adenocarcinoma Of The Stomach

Mucinous Gastric Adenocarcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00991 ARL5A Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ARL5A VGNC VGNC:80139
Macaca mulatta ARL5A VGNC VGNC:70017
Canis familiaris ARL5A VGNC VGNC:38115
Bos taurus ARL5A VGNC VGNC:26147
Mus musculus ARL5A MGD MGI:1922673
Rattus norvegicus ARL5A RGD RGD:621327
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