2. Gene
  3. AK5 - adenylate kinase 5 Gene

AK5 - adenylate kinase 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：腺苷酸激酶 5

种属: Homo sapiens

同用名: AK6

基因 ID: 26289 | 基因类型: protein coding

关于 AK5

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:77,282,019-77,559,966 (from NCBI)

This gene has 13 transcripts (splice variants), 208 orthologues and 9 paralogues. Biased expression in brain (RPKM 40.3) and testis (RPKM 0.8).

功能概要

该基因编码腺苷酸激酶家族的一个成员，该家族通过催化磷酸基团在腺嘌呤核苷酸之间的可逆转移来参与调节细胞内的腺嘌呤核苷酸组成。该成员与几个物种的 UMP/CMP 激酶有关。它位于胞质溶胶中，仅在脑中表达。已经为该基因鉴定了编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

AK5 基因产物(2)

mRNA Protein Name
NM_012093.4 NP_036225.2 adenylate kinase isoenzyme 5 isoform 2
NM_174858.3 NP_777283.1 adenylate kinase isoenzyme 5 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nucleoside diphosphate kinase activity IDA
IDA: 通过直接分析推断
23416111 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

AK5 蛋白结构

ADK

ADK: Adenylate kinase (137 - 293)

ADK

ADK: Adenylate kinase (381 - 536)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 562 a.a.
蛋白主名 其他名称

adenylate kinase isoenzyme 5

AK 5

关联疾病

疾病名称 别名
Limbic Encephalitis
Anterograde Amnesia

Amnesia, Anterograde
Chronic Frontal Sinusitis
Dissociative Amnesia

Psychogenic Amnesia

Amnesia, Dissociative

Amnesia, Psychogenic

Amnesia Neurosis

Hysterical Fugue

Dissociative Fugue
Transient Global Amnesia

Amnesia, Transient Global
Reticular Dysgenesis

Severe Combined Immunodeficiency With Leukopenia

De Vaal Disease

Congenital Aleukia

Aleukocytosis

Hematopoietic Hypoplasia, Generalized

Reticular Dysgenesia

Devaal Disease

Rd

Ak2 Deficiency

Congenital Aleukocytosis

Generalized Hematopoietic Hypoplasia

Scid With Leukopenia

RDYS
Connective Tissue Benign Neoplasm

Soft Tissue Neoplasms

Mesenchymal Tissue Neoplasm

Neoplasm Of Soft Tissue

Neoplasm Of Soft Tissues

Soft Tissue Benign Neoplasm

Tumor Of The Soft Tissue

Soft Tissue Neoplasm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00508 AK5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19858 Ak5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26358 Ak5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris AK5 VGNC VGNC:37747
Rattus norvegicus AK5 RGD RGD:1590818
Macaca mulatta AK5 VGNC VGNC:69762
Bos taurus AK5 VGNC VGNC:25774
Felis catus AK5 VGNC VGNC:59707
Mus musculus AK5 MGD MGI:2677491
Others AK5 NCBI
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