Map2k2 - mitogen-activated protein kinase kinase 2 Gene

中文名称：丝裂原活化蛋白激酶激酶 2

种属: Mus musculus

同用名: MK2; MEK2; Prkmk2

关于 Map2k2

功能概要

该基因编码的蛋白可启动分子适配器活动。参与细胞运动的正调节。作用于多个过程的上游或内部，包括 ERK1 和 ERK2 级联；动物器官发育；和神经元投射发育的调节。位于细胞质中。以多种结构表达，包括消化系统；中枢神经系统;泌尿生殖系统；外皮系统；和感觉器官。该基因的人类直系同源物与心面皮肤综合征 4 和小肠腺癌有关。与人 MAP2K2（丝裂原活化蛋白激酶激酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables molecular adaptor activity. Involved in positive regulation of cell motility. Acts upstream of or within several processes, including ERK1 and ERK2 cascade; animal organ development; and regulation of neuron projection development. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in cardiofaciocutaneous syndrome 4 and small intestine adenocarcinoma. Orthologous to human MAP2K2 (mitogen-activated protein kinase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]