PLEK2 - pleckstrin 2 Gene

中文名称：pleckstrin 2

种属: Homo sapiens

关于 PLEK2

功能概要

该基因编码的蛋白质与磷脂酰肌醇 3-激酶产生的膜结合磷脂酰肌醇相关。然后编码的蛋白质与肌动蛋白细胞骨架相互作用以诱导细胞扩散。结合补体成分 1、q 亚成分、B 链 (C1QB) ，该基因在黑色素瘤细胞中的表达增加，可作为该疾病的准确生物标志物。[RefSeq 提供，2015 年 12 月]

The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin Cytoskeleton to induce cell spreading. In conjunction with Complement Component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]