1. Gene
  2. Rnf31 - ring finger protein 31 Gene

Rnf31 - ring finger protein 31 Gene

种属: Mus musculus

同用名: HOIP; Paul; Flj10111; mFLJ00217

基因 ID: 268749 | 基因类型: protein coding

关于 Rnf31

功能概要

Predicted to enable several functions, including linear polyubiquitin binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin protein Ligase binding activity. Involved in CD40 signaling pathway; positive regulation of I-kappaB kinase/NF-kappaB signaling; and protein ubiquitination. Acts upstream of or within negative regulation of necroptotic process. Located in cytoplasmic side of plasma membrane and cytosol. Part of CD40 receptor complex. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and sensory organ. Orthologous to human RNF31 (ring finger protein 31). [provided by Alliance of Genome Resources, Apr 2022]

Rnf31 基因产物(1)

mRNA Protein Name
NM_194346.3 NP_919327.2 E3 ubiquitin-protein ligase RNF31
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14678832 MGI
enables ubiquitin protein ligase activity IMP
IMP: 通过突变表型推断
19136968 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in CD40 signaling pathway IMP
IMP: 通过突变表型推断
20614026 MGI
acts upstream of or within negative regulation of necroptotic process IGI
IGI: 通过遗传相互作用推断
22089168 MGI
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
19136968 MGI
involved in protein polyubiquitination IMP
IMP: 通过突变表型推断
19136968 MGI
involved in protein ubiquitination IMP
IMP: 通过突变表型推断
20614026 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CD40 receptor complex IDA
IDA: 通过直接分析推断
20614026 MGI
part of LUBAC complex IDA
IDA: 通过直接分析推断
19136968 MGI
located in cytoplasmic side of plasma membrane IDA
IDA: 通过直接分析推断
14678832 MGI
located in cytosol IDA
IDA: 通过直接分析推断
14678832 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase RNF31

HOIL-1-interacting protein

RING-type E3 ubiquitin transferase RNF31

putative Ariadne-like ubiquitin ligase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rnf31 NCBI NCBI:55072