1. Gene
  2. Pon3 - paraoxonase 3 Gene

Pon3 - paraoxonase 3 Gene

种属: Mus musculus

同用名: 2810004E20

基因 ID: 269823 | 基因类型: protein coding

关于 Pon3

功能概要

Predicted to enable 3,4-dihydrocoumarin hydrolase activity; arylesterase activity; and protein homodimerization activity. Involved in negative regulation of superoxide anion generation. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; and atherosclerosis. Orthologous to human PON3 (paraoxonase 3). [provided by Alliance of Genome Resources, Apr 2022]

Pon3 基因产物(9)

mRNA Protein Name
NM_001363812.2 NP_001350741.1 serum paraoxonase/lactonase 3 isoform 2
NM_001411739.1 NP_001398668.1 serum paraoxonase/lactonase 3 isoform 2
NM_001411740.1 NP_001398669.1 serum paraoxonase/lactonase 3 isoform 2
NM_001411741.1 NP_001398670.1 serum paraoxonase/lactonase 3 isoform 2
NM_001411742.1 NP_001398671.1 serum paraoxonase/lactonase 3 isoform 3 precursor
NM_001411743.1 NP_001398672.1 serum paraoxonase/lactonase 3 isoform 4
NM_001411744.1 NP_001398673.1 serum paraoxonase/lactonase 3 isoform 5
NM_001411745.1 NP_001398674.1 serum paraoxonase/lactonase 3 isoform 5
NM_173006.3 NP_766594.1 serum paraoxonase/lactonase 3 isoform 1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of establishment of localization in cell IDA
IDA: 通过直接分析推断
32079677 MGI
acts upstream of establishment of localization in cell IMP
IMP: 通过突变表型推断
32079677 MGI
acts upstream of establishment of localization in cell IPI
IPI: 通过物理相互作用推断
32079677 MGI
involved in negative regulation of superoxide anion generation IDA
IDA: 通过直接分析推断
22441669 MGI
acts upstream of renal sodium ion transport IDA
IDA: 通过直接分析推断
32079677 MGI
acts upstream of renal sodium ion transport IMP
IMP: 通过突变表型推断
32079677 MGI
acts upstream of renal sodium ion transport IPI
IPI: 通过物理相互作用推断
32079677 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

serum paraoxonase/lactonase 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pon3 NCBI NCBI:5446