2. Gene
  3. Irf5 - interferon regulatory factor 5 Gene

Irf5 - interferon regulatory factor 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mirf5

基因 ID: 27056 | 基因类型: protein coding

关于 Irf5

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and protein kinase binding activity. Involved in cytokine-mediated signaling pathway; defense response to Other organism; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in eye; ovary; telencephalon; and urinary system. Human ortholog(s) of this gene implicated in herpes simplex; inflammatory bowel disease 14; multiple sclerosis; rheumatoid arthritis; and systemic lupus erythematosus. Orthologous to human IRF5 (interferon regulatory factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Irf5 基因产物(3)

mRNA Protein Name
NM_001252382.1 NP_001239311.1 interferon regulatory factor 5 isoform 1
NM_001311083.1 NP_001298012.1 interferon regulatory factor 5 isoform 3
NM_012057.4 NP_036187.1 interferon regulatory factor 5 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15665823 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16236719 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
25326420 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytokine-mediated signaling pathway IDA
IDA: 通过直接分析推断
15665823 MGI
involved in defense response to virus IMP
IMP: 通过突变表型推断
20451243 MGI
involved in innate immune response IDA
IDA: 通过直接分析推断
15665823 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15665823 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15665823 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15665823 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon regulatory factor 5

interferon regulatory factor 5 bone marrow

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-149652 IRF5-IN-1 Inhibitor 99.91% 否
HY-150095 YE6144 Inhibitor 96.47% 否
HY-P11003 PTD-N5-1 Inhibitor / 否
HY-P11072 IRF5-CPP5 Inhibitor / 否
HY-RS06909 IRF5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16837 Irf5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23279 Irf5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Irf5 NCBI NCBI:3663
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