1. Gene
  2. TSPAN13 - tetraspanin 13 Gene

TSPAN13 - tetraspanin 13 Gene

中文名称:四跨膜蛋白 13

种属: Homo sapiens

同用名: NET6; NET-6; TM4SF13

基因 ID: 27075 | 基因类型: protein coding

关于 TSPAN13

Cytogenetic location: 7p21.1 Genomic coordinates (GRCh38): 7:16,753,755-16,784,536 (from NCBI)

This gene has 2 transcripts (splice variants), 259 orthologues and 32 paralogues. Broad expression in lung (RPKM 128.5), colon (RPKM 60.3) and 22 other tissues.

功能概要

由该基因编码的蛋白质是跨膜 4 超家族的成员,也称为四跨膜蛋白家族。这些成员中的大多数是细胞表面蛋白,其特征在于存在四个疏水结构域。这些蛋白质介导在细胞发育、活化、生长和运动的调节中起作用的信号转导事件。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]

TSPAN13 基因产物(1)

mRNA Protein Name
NM_014399.4 NP_055214.1 tetraspanin-13

TSPAN13 蛋白结构

Tetraspannin

Tetraspannin: Tetraspanin family (8 - 187)

  • 0
  • 100
  • 204 a.a.
蛋白主名 其他名称

tetraspanin-13

tetraspan NET-6

关联疾病

疾病名称 别名
Intraductal Breast Benign Neoplasm
Intraductal Papilloma

Papilloma, Intraductal

Ductal Papilloma

Papilloma Intraductal

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TSPAN13 VGNC VGNC:47913
Bos taurus TSPAN13 VGNC VGNC:36428
Felis catus TSPAN13 VGNC VGNC:80749
Mus musculus TSPAN13 MGD MGI:1913359
Rattus norvegicus TSPAN13 RGD RGD:1311788
Macaca mulatta TSPAN13 VGNC VGNC:79329