2. Gene
  3. GLG1 - golgi glycoprotein 1 Gene

GLG1 - golgi glycoprotein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：高尔基糖蛋白 1

种属: Homo sapiens

同用名: CFR-1; ESL-1; MG160; MG-160

基因 ID: 2734 | 基因类型: protein coding

关于 GLG1

Cytogenetic location: 16q23.1 Genomic coordinates (GRCh38): 16:74,447,440-74,607,114 (from NCBI)

This gene has 14 transcripts (splice variants) and 284 orthologues. Ubiquitous expression in ovary (RPKM 26.0), testis (RPKM 23.5) and 25 other tissues.

功能概要

预测可启用成纤维细胞生长因子结合活性。预计在几个过程的上游或内部起作用，包括蛋白质加工的负调节；转化生长因子β受体信号通路的负调控；和软骨细胞分化的调节。位于高尔基体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Fibroblast Growth Factor binding activity. Predicted to act upstream of or within several processes, including negative regulation of protein processing; negative regulation of transforming growth factor beta receptor signaling pathway; and regulation of chondrocyte differentiation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

GLG1 基因产物(3)

mRNA Protein Name
NM_001145666.2 NP_001139138.1 Golgi apparatus protein 1 isoform 2 precursor
NM_001145667.2 NP_001139139.1 Golgi apparatus protein 1 isoform 3 precursor
NM_012201.6 NP_036333.2 Golgi apparatus protein 1 isoform 1 precursor

GLG1 蛋白结构

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (154 - 210)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (215 - 273)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (291 - 345)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (349 - 412)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (418 - 470)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (479 - 536)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (540 - 603)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (613 - 667)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (670 - 728)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (732 - 786)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (800 - 855)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (858 - 910)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (915 - 978)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (983 - 1038)

Cys_rich_FGFR

Cys_rich_FGFR: Cysteine rich repeat (1046 - 1100)

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  • 1179 a.a.
蛋白主名 其他名称

Golgi apparatus protein 1

E-selectin ligand 1

关联疾病

疾病名称 别名
Algoneurodystrophy

Reflex Sympathetic Dystrophy

Algoneurodystrophy, Site Unspecified
Pontocerebellar Hypoplasia, Type 2e

Pontocerebellar Hypoplasia Type 2

Pontocerebellar Hypoplasia Type 2e

Pch2

PCH2E

Progressive Microcephaly From Birth Extrapyramidal Dyskinesia Chorea Epilepsy

Pontocerebellar Hypoplasia 2e

Pcca2

Progressive Cerebello-Cerebral Atrophy Type 2

Doid:0112328

Hypoplasia, Pontocerebellar, Type 2e

Pontocerebellar Hypoplasia, Type 2d

Pontocerebellar Hypoplasia Type 2a
Trichinosis

Trichinellosis

Human Trichinellosis

Trichiniasis

Trichinella Spiralis Infection

Infection With Trichinella

Trichinelliasis

Trichinella Spiralis Infestation
Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05471 GLG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21348 Glg1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus GLG1 VGNC VGNC:29398
Rattus norvegicus GLG1 RGD RGD:69345
Mus musculus GLG1 MGD MGI:104967
Macaca mulatta GLG1 VGNC VGNC:73068
Felis catus GLG1 VGNC VGNC:62577
Canis familiaris GLG1 VGNC VGNC:41255
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