1. Gene
  2. Pdhx - pyruvate dehydrogenase complex, component X Gene

Pdhx - pyruvate dehydrogenase complex, component X Gene

种属: Mus musculus

同用名: E3bp; Pdx1

基因 ID: 27402 | 基因类型: protein coding

关于 Pdhx

功能概要

Predicted to enable Acyltransferase activity. Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to act upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Is expressed in several structures, including alimentary system; musculature; nervous system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHX (pyruvate dehydrogenase complex component X). [provided by Alliance of Genome Resources, Apr 2022]

Pdhx 基因产物(1)

mRNA Protein Name
NM_175094.5 NP_780303.1 pyruvate dehydrogenase protein X component, mitochondrial
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acetyl-CoA biosynthetic process from pyruvate IMP
IMP: 通过突变表型推断
17314311 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in mitochondrial matrix IDA
IDA: 通过直接分析推断
9405644 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pyruvate dehydrogenase protein X component, mitochondrial

dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX)

lipoyl-containing pyruvate dehydrogenase complex component X

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdhx NCBI NCBI:8050