2. Gene
  3. Amot - angiomotin Gene

Amot - angiomotin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sii6; CAG-2; D0Kist1

基因 ID: 27494 | 基因类型: protein coding

关于 Amot

功能概要

Predicted to enable angiostatin binding activity and signaling receptor activity. Acts upstream of or within several processes, including ameboidal-type cell migration; negative regulation of GTPase activity; and vasculogenesis. Located in bicellular tight junction; cytoplasmic vesicle; and lamellipodium. Is expressed in several structures, including egg cylinder; embryo endoderm; embryo mesoderm; and mesendoderm. Orthologous to human AMOT (angiomotin). [provided by Alliance of Genome Resources, Apr 2022]

Amot 基因产物(6)

mRNA Protein Name
NM_001290274.2 NP_001277203.1 angiomotin isoform 2
NM_001403386.1 NP_001390315.1 angiomotin isoform 3
NM_001403387.1 NP_001390316.1 angiomotin isoform 1
NM_001403388.1 NP_001390317.1 angiomotin isoform 1
NM_001403389.1 NP_001390318.1 angiomotin isoform 3
NM_153319.4 NP_695231.3 angiomotin isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17397395 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin cytoskeleton organization IMP
IMP: 通过突变表型推断
17699752 MGI
acts upstream of or within blood vessel endothelial cell migration IMP
IMP: 通过突变表型推断
17699752 MGI
acts upstream of or within blood vessel morphogenesis IMP
IMP: 通过突变表型推断
17699752 MGI
acts upstream of or within cell migration involved in gastrulation IMP
IMP: 通过突变表型推断
12676095 MGI
acts upstream of or within chemotaxis IMP
IMP: 通过突变表型推断
12902404 MGI
acts upstream of embryo development IMP
IMP: 通过突变表型推断
12676095 MGI
acts upstream of or within establishment of cell polarity involved in ameboidal cell migration IMP
IMP: 通过突变表型推断
17699752 MGI
acts upstream of or within gastrulation with mouth forming second IMP
IMP: 通过突变表型推断
12676095 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
12676095 MGI
acts upstream of or within negative regulation of GTPase activity IMP
IMP: 通过突变表型推断
17699752 MGI
acts upstream of or within positive regulation of embryonic development IMP
IMP: 通过突变表型推断
12676095 MGI
acts upstream of or within protein localization IMP
IMP: 通过突变表型推断
18824598 MGI
acts upstream of or within regulation of small GTPase mediated signal transduction IMP
IMP: 通过突变表型推断
17699752 MGI
acts upstream of or within vasculogenesis IMP
IMP: 通过突变表型推断
12902404 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in bicellular tight junction IDA
IDA: 通过直接分析推断
17397395 MGI
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
17397395 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
12902404 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

angiomotin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00663 AMOT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20691 Amot Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27202 Amot Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Amot NCBI NCBI:154796
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