1. Gene
  2. Prex1 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Gene

Prex1 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Gene

种属: Mus musculus

同用名: Setd6; P-REX1; G630042G04

基因 ID: 277360 | 基因类型: protein coding

关于 Prex1

功能概要

Predicted to enable phospholipid binding activity. Acts upstream of or within several processes, including neutrophil chemotaxis; positive regulation of GTPase activity; and positive regulation of substrate adhesion-dependent cell spreading. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in several structures, including liver; nervous system; palatal shelf; skeleton; and testis. Used to study autism spectrum disorder. Orthologous to human PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Prex1 基因产物(2)

mRNA Protein Name
NM_177782.3 NP_808450.2 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
NM_177782.3 NP_808450.2 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
21178006 MGI
acts upstream of or within T cell differentiation IGI
IGI: 通过遗传相互作用推断
21178006 MGI
acts upstream of or within neutrophil chemotaxis IGI
IGI: 通过遗传相互作用推断
21179475 MGI
acts upstream of or within positive regulation of GTPase activity IGI
IGI: 通过遗传相互作用推断
21178006 MGI
acts upstream of or within positive regulation of cell adhesion IGI
IGI: 通过遗传相互作用推断
21178006 MGI
acts upstream of or within positive regulation of substrate adhesion-dependent cell spreading IGI
IGI: 通过遗传相互作用推断
21178006 MGI
acts upstream of or within reactive oxygen species metabolic process IGI
IGI: 通过遗传相互作用推断
21179475 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

SET domain containing 6

ptdIns(3,4,5)-dependent Rac exchanger 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prex1 NCBI NCBI:57580