2. Gene
  3. Tinf2 - Terf1 (TRF1)-interacting nuclear factor 2 Gene

Tinf2 - Terf1 (TRF1)-interacting nuclear factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tin2; D14Wsu146e

基因 ID: 28113 | 基因类型: protein coding

关于 Tinf2

功能概要

Enables telomeric DNA binding activity. Acts upstream of or within negative regulation of telomere maintenance. Located in chromosome, telomeric region. Is expressed in several structures, including brain ventricular layer; olfactory epithelium; submandibular gland primordium; thymus primordium; and vibrissa. Used to study dyskeratosis congenita. Human ortholog(s) of this gene implicated in Revesz syndrome and autosomal dominant dyskeratosis congenita 3. Orthologous to human TINF2 (TERF1 interacting nuclear factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tinf2 基因产物(7)

mRNA Protein Name
NM_001404599.1 NP_001391528.1 TERF1-interacting nuclear factor 2 isoform 1
NM_001404600.1 NP_001391529.1 TERF1-interacting nuclear factor 2 isoform 2
NM_001404601.1 NP_001391530.1 TERF1-interacting nuclear factor 2 isoform 4
NM_001404602.1 NP_001391531.1 TERF1-interacting nuclear factor 2 isoform 5
NM_001404603.1 NP_001391532.1 TERF1-interacting nuclear factor 2 isoform 6
NM_001404604.1 NP_001391533.1 TERF1-interacting nuclear factor 2 isoform 7
NM_145705.4 NP_663751.2 TERF1-interacting nuclear factor 2 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12676566 MGI
enables telomeric DNA binding IDA
IDA: 通过直接分析推断
23685356 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of telomere maintenance IDA
IDA: 通过直接分析推断
12676566 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome, telomeric region IDA
IDA: 通过直接分析推断
12676566 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TERF1-interacting nuclear factor 2

TRF1-interacting nuclear factor 2

TRF1-interacting nuclear protein 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14545 TINF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22863 Tinf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29377 Tinf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tinf2 NCBI NCBI:26277
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