2. Gene
  3. Nsun2 - NOL1/NOP2/Sun domain family member 2 Gene

Nsun2 - NOL1/NOP2/Sun domain family member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Misu; D13Wsu123e

基因 ID: 28114 | 基因类型: protein coding

关于 Nsun2

功能概要

Enables mRNA (cytidine-5-)-methyltransferase activity and tRNA (cytosine-5-)-methyltransferase activity. Involved in several processes, including RNA methylation; meiotic cell cycle checkpoint signaling; and tRNA stabilization. Acts upstream of or within in utero embryonic development. Located in chromatoid body. Is expressed in several structures, including branchial arch; cardiovascular system; central nervous system; extraembryonic component; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human NSUN2 (NOP2/Sun RNA methyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Nsun2 基因产物(1)

mRNA Protein Name
NM_145354.5 NP_663329.3 RNA cytosine C(5)-methyltransferase NSUN2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA (cytidine-5-)-methyltransferase activity IDA
IDA: 通过直接分析推断
23871666 MGI
enables tRNA (cytidine-5-)-methyltransferase activity IDA
IDA: 通过直接分析推断
23871666 MGI
enables tRNA (cytidine-5-)-methyltransferase activity IMP
IMP: 通过突变表型推断
22885326 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within hair follicle maturation IMP
IMP: 通过突变表型推断
25340873 MGI
involved in hair follicle maturation IMP
IMP: 通过突变表型推断
22144916 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
27996060 MGI
involved in mRNA processing IDA
IDA: 通过直接分析推断
23871666 MGI
involved in meiotic cell cycle checkpoint signaling IMP
IMP: 通过突变表型推断
23401851 MGI
involved in regulation of stem cell differentiation IMP
IMP: 通过突变表型推断
22144916 MGI
involved in spermatid development IMP
IMP: 通过突变表型推断
23401851 MGI
involved in tRNA methylation IDA
IDA: 通过直接分析推断
31276587 MGI
involved in tRNA methylation IMP
IMP: 通过突变表型推断
22144916 MGI
involved in tRNA processing IDA
IDA: 通过直接分析推断
23871666 MGI
involved in tRNA stabilization IMP
IMP: 通过突变表型推断
22885326 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatoid body IDA
IDA: 通过直接分析推断
23401851 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

RNA cytosine C(5)-methyltransferase NSUN2

Myc-induced SUN domain containing protein

NOL1/NOP2/Sun domain family 2

mRNA cytosine C(5)-methyltransferase

myc-induced SUN domain-containing protein

tRNA (cytosine(34)-C(5))-methyltransferase

tRNA (cytosine-5-)-methyltransferase NSUN2

tRNA cytosin

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158301 MY-1B Inhibitor 99.94% 否
HY-RS29442 Nsun2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS09601 NSUN2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24549 Nsun2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nsun2 NCBI NCBI:54888
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