2. Gene
  3. GPR12 - G protein-coupled receptor 12 Gene

GPR12 - G protein-coupled receptor 12 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白偶联受体 12

种属: Homo sapiens

同用名: GPCR12; GPCR21; PPP1R84

基因 ID: 2835 | 基因类型: protein coding

关于 GPR12

Cytogenetic location: 13q12.13 Genomic coordinates (GRCh38): 13:26,755,200-26,760,786 (from NCBI)

This gene has 2 transcripts (splice variants), 192 orthologues and 18 paralogues. Biased expression in brain (RPKM 3.0) and salivary gland (RPKM 0.6).

功能概要

预计可启用 G 蛋白偶联受体活性。预计参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路和代谢过程的调控。预测作用于 G 蛋白偶联受体信号通路和细胞钙离子稳态的上游或内部。预计是质膜的组成部分。预计在细胞质和质膜中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and cellular calcium ion homeostasis. Predicted to be integral component of plasma membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR12 基因产物(1)

mRNA Protein Name
NM_005288.4 NP_005279.1 G-protein coupled receptor 12

GPR12 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (61 - 301)

  • 0
  • 100
  • 200
  • 300
  • 334 a.a.
蛋白主名 其他名称

G-protein coupled receptor 12

protein phosphatase 1, regulatory subunit 84

关联疾病

疾病名称 别名
Vulvar Dystrophy

Dystrophy Of Vulva
Lennox-Gastaut Syndrome

Lennox Syndrome

Encephalopathy Of Childhood

Epileptic Encephalopathy Lennox-Gastaut Type

Childhood Epileptic Encephalopathy With Diffuse Slow Spikes And Waves

Lgs
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-108496 Sphingosine-1-phosphate Agonist 99.54% Phase 1
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108496S Sphingosine-1-phosphate-d7 Agonist 99.00% 否
HY-RS05655 GPR12 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20031 Gpr12 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26534 Gpr12 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris GPR12 VGNC VGNC:41395
Felis catus GPR12 VGNC VGNC:67414
Macaca mulatta GPR12 VGNC VGNC:106264
Rattus norvegicus GPR12 RGD RGD:68333
Mus musculus GPR12 MGD MGI:101909
Bos taurus GPR12 VGNC VGNC:29547
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