2. Gene
  3. PROX2 - prospero homeobox 2 Gene

PROX2 - prospero homeobox 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：普洛斯彼罗同源盒 2

种属: Homo sapiens

同用名: PROX-2

基因 ID: 283571 | 基因类型: protein coding

关于 PROX2

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:74,853,033-74,876,145 (from NCBI)

This gene has 3 transcripts (splice variants), 263 orthologues and 1 paralogue. Low expression observed in reference dataset.

功能概要

预测可实现 DNA 结合转录因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调节区序列特异性 DNA 结合活性。预计参与 RNA 聚合酶 II 的转录调控。预测是染色质的一部分。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PROX2 基因产物(3)

mRNA Protein Name
NM_001080408.3 NP_001073877.2 prospero homeobox protein 2 isoform 2
NM_001243007.2 NP_001229936.1 prospero homeobox protein 2 isoform 1
NM_001384314.1 NP_001371243.1 prospero homeobox protein 2 isoform 1

PROX2 蛋白结构

HPD

HPD: Homeo-prospero domain (439 - 590)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 592 a.a.
蛋白主名 其他名称

prospero homeobox protein 2

homeobox prospero-like protein PROX2

关联疾病

疾病名称 别名
Atrial Septal Defect 6

ASD6

Atrial Heart Septal Defect 6

Septal Defect, Atrial, Type 6
Atrial Septal Defect 5

ASD5

Atrial Heart Septal Defect 5

Septal Defect, Atrial, Type 5
Congenital Central Hypoventilation Syndrome

Cchs

Haddad Syndrome

Ondine Curse

Ondine Syndrome

Congenital Central Hypoventilation

Congenital Central Alveolar Hypoventilation Syndrome

Congenital Failure Of Autonomic Control

Ondine'S Curse

Primary Alveolar Hypoventilation

Ondine-Hirschsprung Disease

Central Congenital Hypoventilation Syndrome

Congenital Ondine Curse

Idiopathic Congenital Central Alveolar Hypoventilation

Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome

Ondine-Hirschsprung Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11204 PROX2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PROX2 VGNC VGNC:99228
Canis familiaris PROX2 VGNC VGNC:45018
Mus musculus PROX2 MGD MGI:1920672
Bos taurus PROX2 VGNC VGNC:33370
Felis catus PROX2 VGNC VGNC:64368
Rattus norvegicus PROX2 RGD RGD:1310315
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