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  2. P2RY8 - P2Y receptor family member 8 Gene

P2RY8 - P2Y receptor family member 8 Gene

中文名称:P2Y 受体家族成员 8

种属: Homo sapiens

同用名: P2Y8

基因 ID: 286530 | 基因类型: protein coding

关于 P2RY8

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:1,462,581-1,537,185 (from NCBI)

This gene has 2 transcripts (splice variants), 163 orthologues, 16 paralogues and is associated with 46 phenotypes. Broad expression in lymph node (RPKM 13.9), spleen (RPKM 8.9) and 14 other tissues.

功能概要

该基因编码的蛋白质属于 G 蛋白偶联受体家族,优先被腺苷和尿苷核苷酸激活。该基因在未分化的 HL60 细胞中适度表达,位于 X 和 Y 染色体上。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008]

P2RY8 基因产物(1)

mRNA Protein Name
NM_178129.5 NP_835230.1 P2Y purinoceptor 8

P2RY8 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (40 - 293)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
蛋白主名 其他名称

P2Y purinoceptor 8

G-protein coupled purinergic receptor P2Y8

P2RY8 抗体

目录号 产品名 应用 反应物种
HY-P84661 P2RY8 Antibody (YA4358) IHC-P, ICC/IF, FC, ELISA Human

关联疾病

疾病名称 别名
B-Lymphoblastic Leukemia/Lymphoma With Iamp21

B-All With Iamp21

Intrachromosomal Amplification Of Chromosome 21

Intellectual Developmental Disorder, Autosomal Dominant 33

MRD33

Autosomal Dominant Non-Syndromic Intellectual Disability 33

Mental Retardation, Autosomal Dominant 33

Autosomal Dominant Intellectual Developmental Disorder 33

Autosomal Dominant Mental Retardation 33

Mental Retardation, Autosomal Dominant, Type 33

Plasma Cell Neoplasm

Plasma Cell Dyscrasia

Paraproteinemias

Plasma Cell Tumour

Plasmacytic Tumor

Multiple Myeloma

Plasmacytoma

Plasma Cell Tumours

Plasma Cells Dyscrasia

Myeloma, Multiple

Multiple Myeloma

Plasma Cell Myeloma

Kahler Disease

Myelomatosis

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Kahler'S Disease

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

B-Lymphoblastic Leukemia/Lymphoma With Etv6-Runx1

B-All With Etv6-Runx1

B-Lymphoblastic Leukemia/Lymphoma With T(12

21)(P13.2

Q22.1)

Etv6-Runx1

B Lymphoblastic Leukemia/Lymphoma With T(12

21)(P13.2

Q22.1)

Etv6-Runx1

Childhood B-Cell Acute Lymphoblastic Leukemia

B-Cell Childhood Acute Lymphoblastic Leukemia

Chromosomal Duplication Syndrome
B-Lymphoblastic Leukemia/Lymphoma

B Lymphoblastic Leukemia/Lymphoma

B-All

Precursor B Lymphoblastic Lymphoma/Leukemia

C-All

Lymphoblastic Lymphoma, Nos

Common Precursor B All

Lymphoblastic B-Cell Lymphoma

Pro-B All

B-Precursor Lymphoma

Lbl - [Lymphoblastic Lymphoma]

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca fascicularis P2RY8 NCBI NCBI:102115913
Mus musculus P2RY8 NCBI