Aspm - assembly factor for spindle microtubules Gene

种属: Rattus norvegicus

同用名: Calmbp1

关于 Aspm

功能概要

Predicted to enable Calmodulin binding activity. Predicted to be involved in regulation of meiotic cell cycle; spindle localization; and spindle organization. Predicted to act upstream of or within several processes, including gamete generation; maintenance of centrosome location; and nervous system development. Located in apical plasma membrane; microtubule cytoskeleton; and midbody. Human ortholog(s) of this gene implicated in microcephaly; primary autosomal recessive microcephaly; primary autosomal recessive microcephaly 5; and visual epilepsy. Orthologous to human ASPM (assembly factor for spindle microtubules). [provided by Alliance of Genome Resources, Apr 2022]