1. Gene
  2. Chat - choline O-acetyltransferase Gene

Chat - choline O-acetyltransferase Gene

种属: Rattus norvegicus

基因 ID: 290567 | 基因类型: protein coding

关于 Chat

功能概要

Enables choline O-acetyltransferase activity and choline binding activity. Involved in several processes, including acetylcholine biosynthetic process; antral ovarian follicle growth; and response to ethanol. Located in neuron projection. Biomarker of Alzheimer's disease and asthma. Human ortholog(s) of this gene implicated in Alzheimer's disease and congenital myasthenic syndrome 6. Orthologous to human CHAT (choline O-acetyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Chat 基因产物(1)

mRNA Protein Name
NM_001170593.1 NP_001164064.1 choline O-acetyltransferase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables choline O-acetyltransferase activity IDA
IDA: 通过直接分析推断
126256 RGD
enables choline binding IDA
IDA: 通过直接分析推断
126256 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acetylcholine biosynthetic process IDA
IDA: 通过直接分析推断
126256 RGD
involved in antral ovarian follicle growth IEP
IEP: 通过表达模式推断
16846505 RGD
involved in memory IMP
IMP: 通过突变表型推断
16854393 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
17045751 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
17218023 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
17192613 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17374747 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

choline O-acetyltransferase

CHOACTase

choline acetylase

choline acetyltransferase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chat NCBI NCBI:1103