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  2. SCG3 - secretogranin III Gene

SCG3 - secretogranin III Gene

中文名称:分泌粒素 III

种属: Homo sapiens

同用名: SGIII

基因 ID: 29106 | 基因类型: protein coding

关于 SCG3

Cytogenetic location: 15q21.2 Genomic coordinates (GRCh38): 15:51,681,503-51,721,026 (from NCBI)

This gene has 3 transcripts (splice variants) and 203 orthologues. Biased expression in brain (RPKM 94.6), adrenal (RPKM 8.5) and 1 other tissue.

功能概要

由该基因编码的蛋白质是神经内分泌蛋白嗜铬粒蛋白/分泌粒蛋白家族的成员。颗粒蛋白可以作为生物活性肽的前体。一些颗粒蛋白已被证明在激素原的分选和蛋白水解过程中起辅助蛋白的作用;然而,这种蛋白质的功能是未知的。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供,2009 年 9 月]

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

SCG3 基因产物(2)

mRNA Protein Name
NM_001165257.2 NP_001158729.1 secretogranin-3 isoform 2
NM_013243.4 NP_037375.2 secretogranin-3 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SCG3 蛋白结构

SGIII

SGIII: Secretogranin-3 (17 - 468)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 468 a.a.
蛋白主名 其他名称

secretogranin-3

SCG3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SCG3 Q8WXD2 SDCBP Homo sapiens O00560 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 SCG3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71279 SCG3/Secretogranin-3 Protein, Human (HEK293, His) Q8WXD2-1 (F20-L468) ≥95%
HY-P74568 SCG3/Secretogranin-3 Protein, Human (HEK293, His, solution) Q8WXD2-1 (F20-L468) ≥95%

关联疾病

疾病名称 别名
Motility-Related Diarrhea
Exudative Vitreoretinopathy 1

Retinopathy Of Prematurity

Retrolental Fibroplasia

EVR1

Criswick-Schepens Syndrome

Rop

Exudative Vitreoretinopathy, Familial, Autosomal Dominant

Fevr, Autosomal Dominant

Premature Retinopathy

Vitreoretinopathy, Exudative 1

Autosomal Dominant Familial Exudative Vitreoretinopathy

Fevr

Vitreoretinopathy, Exudative, Type 1

Retinopathy Of Prematurity Nos

Rlf- [Retrolental Fibroplasia]

Rop - [Retinopathy Of Prematurity]

Terry Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SCG3 VGNC VGNC:34333
Canis familiaris SCG3 VGNC VGNC:45906
Rattus norvegicus SCG3 RGD RGD:621209
Mus musculus SCG3 MGD MGI:103032
Macaca mulatta SCG3 VGNC VGNC:77013
Felis catus SCG3 VGNC VGNC:64909
Macaca fascicularis SCG3 NCBI NCBI:101925820
Others SCG3 NCBI