2. Gene
  3. Nedd4l - NEDD4 like E3 ubiquitin protein ligase Gene

Nedd4l - NEDD4 like E3 ubiquitin protein ligase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Nedd4-2

基因 ID: 291553 | 基因类型: protein coding

关于 Nedd4l

功能概要

Enables Potassium Channel Inhibitor activity and ubiquitin-protein transferase activity. Involved in several processes, including positive regulation of caveolin-mediated endocytosis; protein monoubiquitination; and ventricular cardiac muscle cell action potential. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human NEDD4L (NEDD4 like E3 ubiquitin protein Ligase). [provided by Alliance of Genome Resources, Apr 2022]

Nedd4l 基因产物(1)

mRNA Protein Name
NM_001401320.1 NP_001388249.1 E3 ubiquitin-protein ligase NEDD4-like
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables potassium channel inhibitor activity IMP
IMP: 通过突变表型推断
22879586 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
22417925 RGD
enables ubiquitin-protein transferase activity IDA
IDA: 通过直接分析推断
19953087 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of potassium ion transmembrane transporter activity IMP
IMP: 通过突变表型推断
22879586 RGD
involved in positive regulation of caveolin-mediated endocytosis IMP
IMP: 通过突变表型推断
22879586 RGD
involved in positive regulation of protein catabolic process IMP
IMP: 通过突变表型推断
18174164 RGD
involved in protein monoubiquitination IMP
IMP: 通过突变表型推断
21332718 RGD
involved in ventricular cardiac muscle cell action potential IMP
IMP: 通过突变表型推断
22879586 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase NEDD4-like

neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09180 NEDD4L Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17116 Nedd4l Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23561 Nedd4l Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nedd4l NCBI NCBI:23327
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z