1. Gene
  2. Lars1 - leucyl-tRNA synthetase 1 Gene

Lars1 - leucyl-tRNA synthetase 1 Gene

种属: Rattus norvegicus

同用名: Lars

基因 ID: 291624 | 基因类型: protein coding

关于 Lars1

功能概要

Predicted to enable GTPase activator activity; glutamine-tRNA Ligase activity; and leucine-tRNA Ligase activity. Predicted to be involved in several processes, including cellular response to leucine; cellular response to leucine starvation; and tRNA aminoacylation for protein translation. Predicted to be located in several cellular components, including endoplasmic reticulum; lysosome; and nuclear body. Predicted to be part of Aminoacyl-tRNA Synthetase multienzyme complex. Human ortholog(s) of this gene implicated in infantile liver failure syndrome 1. Orthologous to human LARS1 (leucyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Lars1 基因产物(1)

mRNA Protein Name
NM_001009637.1 NP_001009637.1 leucine--tRNA ligase, cytoplasmic
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
27191843 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

leucine--tRNA ligase, cytoplasmic

leucyl-tRNA synthetase, cytoplasmic

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lars1 NCBI NCBI:51520