1. Gene
  2. Vtn - vitronectin Gene

Vtn - vitronectin Gene

种属: Rattus norvegicus

同用名: Vn; Aa1018

基因 ID: 29169 | 基因类型: protein coding

关于 Vtn

功能概要

Enables Collagen binding activity; heparin binding activity; and identical protein binding activity. Involved in liver regeneration and protein polymerization. Located in several cellular components, including Golgi lumen; basement membrane; and rough endoplasmic reticulum lumen. Used to study proteinuria. Biomarker of diabetic retinopathy and visual epilepsy. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Orthologous to human VTN (Vitronectin). [provided by Alliance of Genome Resources, Apr 2022]

Vtn 基因产物(1)

mRNA Protein Name
NM_019156.2 NP_062029.2 vitronectin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables collagen binding IDA
IDA: 通过直接分析推断
10988248 RGD
enables heparin binding IDA
IDA: 通过直接分析推断
8804356 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
17369286 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in liver regeneration IDA
IDA: 通过直接分析推断
10988248 RGD
involved in protein polymerization IDA
IDA: 通过直接分析推断
17369286 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi lumen IDA
IDA: 通过直接分析推断
10192552 RGD
located in basement membrane IDA
IDA: 通过直接分析推断
11728964 RGD
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
2426279 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
17567740 RGD
located in rough endoplasmic reticulum lumen IDA
IDA: 通过直接分析推断
10192552 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

vitronectin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vtn NCBI NCBI:7448
Mus musculus Vtn NCBI NCBI:22370