1. Gene
  2. Rbbp8 - RB binding protein 8, endonuclease Gene

Rbbp8 - RB binding protein 8, endonuclease Gene

种属: Rattus norvegicus

同用名: RIM; CtIP; SAE2; RBBP-8; RGD1308872

基因 ID: 291787 | 基因类型: protein coding

关于 Rbbp8

功能概要

Predicted to enable several functions, including DNA binding activity; identical protein binding activity; and single-stranded DNA endodeoxyribonuclease activity. Involved in response to estradiol. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in site of double-strand break. Human ortholog(s) of this gene implicated in Seckel syndrome 2. Orthologous to human RBBP8 (RB binding protein 8, Endonuclease). [provided by Alliance of Genome Resources, Apr 2022]

Rbbp8 基因产物(1)

mRNA Protein Name
NM_001134417.1 NP_001127889.1 DNA endonuclease RBBP8
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to estradiol IEP
IEP: 通过表达模式推断
15473135 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

DNA endonuclease RBBP8

ctBP-interacting protein

retinoblastoma binding protein 8

sporulation in the absence of SPO11 protein 2 homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rbbp8 NCBI NCBI:5932