2. Gene
  3. Areg - amphiregulin Gene

Areg - amphiregulin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29183 | 基因类型: protein coding

关于 Areg

功能概要

Enables epidermal growth factor receptor binding activity and growth factor activity. Involved in several processes, including negative regulation of osteoblast differentiation; neurogenesis; and response to cAMP. Located in extracellular space. Used to study high grade glioma. Human ortholog(s) of this gene implicated in breast Cancer. Orthologous to human AREG (Amphiregulin). [provided by Alliance of Genome Resources, Apr 2022]

Areg 基因产物(1)

mRNA Protein Name
NM_017123.2 NP_058819.1 amphiregulin preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables epidermal growth factor receptor binding IDA
IDA: 通过直接分析推断
15509566 RGD
enables growth factor activity IDA
IDA: 通过直接分析推断
2234093 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epidermal growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
15509566 RGD
involved in glial cell proliferation IDA
IDA: 通过直接分析推断
2234093 RGD
involved in negative regulation of osteoblast differentiation IDA
IDA: 通过直接分析推断
15509566 RGD
involved in neuron projection development IMP
IMP: 通过突变表型推断
1530950 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
15509566 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
8621257 RGD
involved in positive regulation of phosphorylation IDA
IDA: 通过直接分析推断
15509566 RGD
involved in response to cAMP IEP
IEP: 通过表达模式推断
16088955 RGD
involved in response to glucocorticoid IMP
IMP: 通过突变表型推断
1530950 RGD
involved in response to hydrogen peroxide IEP
IEP: 通过表达模式推断
8806670 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
16088955 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
16088955 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
2234093 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

amphiregulin

AR

SDGF

schwannoma-derived growth factor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00892 AREG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17019 Areg Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23462 Areg Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Areg NCBI NCBI:374
Mus musculus Areg NCBI NCBI:11839
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