1. Gene
  2. Aars1 - alanyl-tRNA synthetase 1 Gene

Aars1 - alanyl-tRNA synthetase 1 Gene

种属: Rattus norvegicus

同用名: Aars

基因 ID: 292023 | 基因类型: protein coding

关于 Aars1

功能概要

Enables several functions, including ATP binding activity; alanine-tRNA Ligase activity; and tRNA binding activity. Involved in alanyl-tRNA aminoacylation. Located in cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2N and developmental and epileptic encephalopathy 29. Orthologous to human AARS1 (alanyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Aars1 基因产物(1)

mRNA Protein Name
NM_001100517.1 NP_001093987.1 alanine--tRNA ligase, cytoplasmic
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IPI
IPI: 通过物理相互作用推断
2040280 RGD
enables alanine-tRNA ligase activity IDA
IDA: 通过直接分析推断
2040280 RGD
enables amino acid binding IPI
IPI: 通过物理相互作用推断
2040280 RGD
enables tRNA binding IPI
IPI: 通过物理相互作用推断
2040280 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in alanyl-tRNA aminoacylation IDA
IDA: 通过直接分析推断
2040280 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

alanine--tRNA ligase, cytoplasmic

alaRS

alanyl-tRNA synthetase, cytoplasmic

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aars1 NCBI NCBI:16
Mus musculus Aars1 NCBI