Cdt1 - chromatin licensing and DNA replication factor 1 Gene

种属: Rattus norvegicus

同用名: Ris2

关于 Cdt1

功能概要

Predicted to enable DNA binding activity; DNA Polymerase binding activity; and chromatin binding activity. Predicted to be involved in several processes, including regulation of DNA-dependent DNA replication; regulation of cell cycle phase transition; and regulation of protein localization to kinetochore. Predicted to act upstream of or within regulation of nuclear cell cycle DNA replication. Predicted to be located in kinetochore and nuclear body. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1). [provided by Alliance of Genome Resources, Apr 2022]