1. Gene
  2. Cbr1 - carbonyl reductase 1 Gene

Cbr1 - carbonyl reductase 1 Gene

种属: Rattus norvegicus

同用名: Cbr; PG-9-KR

基因 ID: 29224 | 基因类型: protein coding

关于 Cbr1

功能概要

Enables carbonyl reductase (NADPH) activity. Involved in several processes, including ovulation from ovarian follicle; phylloquinone catabolic process; and prostaglandin catabolic process. Located in microvillus; nucleus; and plasma membrane. Biomarker of chronic kidney disease. Orthologous to human CBR1 (carbonyl reductase 1). [provided by Alliance of Genome Resources, Apr 2022]

Cbr1 基因产物(1)

mRNA Protein Name
NM_019170.2 NP_062043.1 carbonyl reductase [NADPH] 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carbonyl reductase (NADPH) activity IDA
IDA: 通过直接分析推断
7705364 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
24882364 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ovulation from ovarian follicle IEP
IEP: 通过表达模式推断
10642578 RGD
involved in phylloquinone catabolic process IDA
IDA: 通过直接分析推断
16359670 RGD
involved in prostaglandin catabolic process IDA
IDA: 通过直接分析推断
7705364 RGD
involved in response to estradiol IDA
IDA: 通过直接分析推断
3796215 RGD
involved in response to gonadotropin IEP
IEP: 通过表达模式推断
12444039 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
12399253 RGD
involved in response to progesterone IDA
IDA: 通过直接分析推断
3796215 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
16457595 RGD
involved in steroid catabolic process IDA
IDA: 通过直接分析推断
7705364 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in microvillus IDA
IDA: 通过直接分析推断
16457595 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

carbonyl reductase [NADPH] 1

15-hydroxyprostaglandin dehydrogenase

20-beta-hydroxysteroid dehydrogenase

Cbr 1

NADPH-dependent carbonyl reductase 1

alcohol dehydrogenase [NAD(P)+] CBR1

prostaglandin 9-ketoreductase

prostaglandin-E(2) 9-reductase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cbr1 NCBI NCBI:873